| Synonyms: |
1-Chloro-2-Deoxy-3,5-Di(O-P-Chlorobenzoyl)-D-Ribofuranose;2-Deoxy-3,5-bis-O-(4-chlorobenzoyl)-D-erythro-pent;3,5-O-Bis(4-chlorobenzoyl)-2-deoxy-D-ribofuranosyl;1-Chloro-3,5-Di-(P-Chlorobenzo;1-CHLORO-3,5-DIPARACHLOROBENZOYL-2-DEOXY-D-RIBOSE;1-Chloro-2-deoxy-3,5-bi (O-p-aldylbenzoyl)-D-ribofuranose;1-CHLORO-3,5-DI(4-CHLORBENZOYL)-2-DEOXY-D-RIBOSE;3,5-O-Bis(4-chlorobenzoyl)-2-deoxy-D-ribofuranosyl chloride |
Item |
Quality Index |
Appearance |
Off-white to slightly yellow poeder |
Purity |
>=98% |
Application |
1-Chloro-3,5-di(4-chlorbenzoyl)-2-deoxy-D-ribose(Cas No.:3601-90-9) is an intermediate in medicinal chemistry and organic synthesis, for example, it can be used in the preparation and synthesis of drug molecules decitabine, decitabine It is a natural adenosine analogue of 2′-deoxycytidine acid, which can reduce DNA methylation by inhibiting DNA methyltransferase, thereby inhibiting tumor cell proliferation and preventing the occurrence of drug resistance. It is currently the most known A strong DNA methylation-specific inhibitor, which belongs to the S-phase cell cycle-specific drug, and is suitable for the treatment of myelodysplastic syndrome (MDS). |
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