3-Hydroxypiperidine(Cas No.:6859-99-0) can be used to produce 3-hydroxy-piperidine-1-carbonyl chloride at the temperature of -65 °C. It will need reagent triethylamine and solvent CH2Cl2 with the reaction time of 15 hours. The yield is about 87%.
3-Hydroxypiperidine(Cas No.:6859-99-0) is usually used for synthesis of piperidine nucleoside analogs,Fluorination reactions,synthesis of substituted pyridines.
3-Hydroxypiperidine(Cas No.:6859-99-0) is used as a reagent to synthesize trisubstituted ureas, compounds that act as thrombin receptor (PAR-1) antagonists. |